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South Carolina Department of Revenue
Registration

Columbia, SC 29214-0140

Phone: 803-896-1350
Email: TaxRegistration@dor.sc.gov

If the service you are providing is not one of the specifically taxed services under the sales and use tax, then you would not need a retail license.

To see a list of the services that may be taxable go to: http://www.scstatehouse.gov/coderegs/Ch ​​117.pdf​ From there go to Regulations 117-308 to find this list.